Traduction: G.M.
J Autism Dev Disord. 2017 Jun 14. doi: 10.1007/s10803-017-3193-2.
Respiratory Sinus Arrhythmia Predicts Restricted Repetitive Behavior Severity
Condy EE1, Scarpa A2, Friedman BH2.
Author information
- 1
- Department of Psychology (0436), Virginia Polytechnic Institute and State University, 109 Williams Hall, Blacksburg, VA, 24061, USA. econdy@vt.edu.
- 2
- Department of Psychology (0436), Virginia Polytechnic Institute and State University, 109 Williams Hall, Blacksburg, VA, 24061, USA.
Abstract
En
plus des déficits de communication sociale, les comportements
répétitifs restreints (RRB) sont une caractéristique diagnostique clé du
"trouble du spectre de l'autisme" (TSA). La dysfonction du système nerveux autonome (ANS) dans le TSA a été avancée comme un mécanisme de RRB; Cependant,
la plupart des études sur l'activité ANS dans les TSA se sont
concentrées sur leur relation avec le fonctionnement social. Cette
étude a utilisé des modèles d'arythmie des sinus respiratoires (RSA)
pour mesurer le fonctionnement de l'ANS et analyser sa relation avec les
RRB chez les enfants avec ou sans diagnostic de TSA. La
ligne de base du RSA et la réactivité du RSA ont prédit la gravité du RRB et les analyses
exploratoires ont révélé que ces mesures peuvent être associées aux
sous-groupes RRB. Ces résultats sont discutés en ce qui concerne la littérature
comportementale sur les RRB et les avantages de trouver des biomarqueurs
pour ces comportements.
In addition to social communication deficits, restricted repetitive behaviors (RRBs) are a key diagnostic feature of autism spectrum disorder (ASD). Dysfunction of the autonomic nervous system (ANS) in ASD has been posited as a mechanism of RRBs; however, most studies investigating ANS activity in ASD have focused on its relation to social functioning. This study used respiratory sinus arrhythmia (RSA) patterns to measure ANS functioning and analyze its relation to RRBs in children with and without an ASD diagnosis. Baseline RSA and RSA reactivity predicted RRB severity and exploratory analyses revealed these measures may be associated with RRB subgroups. These results are discussed in regards to the behavioral literature on RRBs and the benefits of finding biomarkers for these behaviors.
In addition to social communication deficits, restricted repetitive behaviors (RRBs) are a key diagnostic feature of autism spectrum disorder (ASD). Dysfunction of the autonomic nervous system (ANS) in ASD has been posited as a mechanism of RRBs; however, most studies investigating ANS activity in ASD have focused on its relation to social functioning. This study used respiratory sinus arrhythmia (RSA) patterns to measure ANS functioning and analyze its relation to RRBs in children with and without an ASD diagnosis. Baseline RSA and RSA reactivity predicted RRB severity and exploratory analyses revealed these measures may be associated with RRB subgroups. These results are discussed in regards to the behavioral literature on RRBs and the benefits of finding biomarkers for these behaviors.
- PMID:28616855
- DOI:10.1007/s10803-017-3193-2
