Aperçu: G.M.
Les
systèmes liés à l'oxytocine et à la vasopressine sont présents chez les
animaux invertébrés et vertébrés, y compris les
humains, et présentent des propriétés neuroanatomiques et fonctionnelles
conservées. Chez les vertébrés, ces systèmes inervent des réseaux de neurones conservés
qui régulent l'apprentissage social et le comportement, y compris la
reconnaissance conspécifique, l'attachement social et le comportement
des parents.
L'étude décrit les caractéristiques conservées et variables des systèmes centraux
d'ocytocine et de vasopressine dans le contexte de la diversité sociale
du comportement, en mettant particulièrement l'accent sur les réseaux
neuronaux qui modulent l'apprentissage social, le comportement et la
souplesse des stimulants socio-sensoriels dans les contextes sociaux
typiques des espèces.
Neurosci Biobehav Rev. 2017 May;76(Pt A):87-98. doi: 10.1016/j.neubiorev.2017.01.034.
Oxytocin and vasopressin neural networks: Implications for social behavioral diversity and translational neuroscience
Johnson ZV1, Young LJ2.
Author information
- 1
- Silvio O. Conte Center for Oxytocin and Social Cognition, Center for Translational Social Neuroscience, Department of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA; School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA. Electronic address: zjohnso2@gmail.com
- 2
- Silvio O. Conte Center for Oxytocin and Social Cognition, Center for Translational Social Neuroscience, Department of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA. Electronic address: lyoun03@emory.edu.
Abstract
Oxytocin-
and vasopressin-related systems are present in invertebrate and
vertebrate bilaterian animals, including humans, and exhibit conserved
neuroanatomical and functional properties. In vertebrates, these systems
innervate conserved neural networks that regulate social learning and
behavior, including conspecific recognition, social attachment, and
parental behavior. Individual and species-level variation in central
organization of oxytocin and vasopressin systems has been linked to
individual and species variation in social learning and behavior. In
humans, genetic polymorphisms in the genes encoding oxytocin and
vasopressin peptides and/or their respective target receptors have been
associated with individual variation in social recognition, social
attachment phenotypes, parental behavior, and psychiatric phenotypes
such as autism.
Here we describe both conserved and variable features of central
oxytocin and vasopressin systems in the context of social behavioral
diversity, with a particular focus on neural networks that modulate
social learning, behavior, and salience of sociosensory stimuli during
species-typical social contexts.
Published by Elsevier Ltd.
- PMID: 28434591
- DOI: 10.1016/j.neubiorev.2017.01.034
