Aperçu: G.M.
Plusieurs
applications existent pour une image de cerveau de tomographie par
émission de positons (PET) entièrement conçue comme une unité portable
qui peut être portée sur la tête d'un patient. Grâce
à l'amélioration de la technologie des détecteurs, un appareil léger et
performant permettrait l'imagerie du cerveau PET dans différents
environnements et pendant les tâches comportementales. Un
tel système portatif qui permet aux sujets de se déplacer et de marcher
- le PET ambulatoire Microdose (AM-PET) - est en cours de
développement.
Sensors (Basel). 2017 May 19;17(5). pii: E1164. doi: 10.3390/s17051164.
Development and Design of Next-Generation Head-Mounted Ambulatory Microdose Positron-Emission Tomography (AM-PET) System
Melroy S1, Bauer C2, McHugh M3, Carden G4, Stolin A5, Majewski S6, Brefczynski-Lewis J7, Wuest T8.
Author information
- 1
- Industrial and Management Systems Engineering, West Virginia University, Morgantown, WV 26506, USA. smelroy@mix.wvu.edu
- 2
- Montgomery-Downs Lab, Blanchette Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV 26506, USA. cbauer5@mix.wvu.edu.
- 3
- Mechanical and Aerospace Engineering, West Virginia University, Morgantown, WV 26506, USA. mmchugh4@mix.wvu.edu.
- 4
- Industrial and Management Systems Engineering, West Virginia University, Morgantown, WV 26506, USA. gtcarden@mix.wvu.edu.
- 5
- Department of Radiology, Center for Advanced Imaging, West Virginia University, Morgantown, WV 26506, USA. astolin@hsc.wvu.edu.
- 6
- Department of Radiology & Medical Imaging, University of Virginia, Charlottesville, VA 22903, USA. sm4aa@virginia.edu.
- 7
- Physiology & Pharmacology & Blanchette Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV 26506, USA. jblewis@hsc.wvu.edu.
- 8
- Industrial and Management Systems Engineering, West Virginia University, Morgantown, WV 26506, USA. thwuest@mail.wvu.edu.
Abstract
Several
applications exist for a whole brain positron-emission tomography (PET)
brain imager designed as a portable unit that can be worn on a
patient's head. Enabled by improvements in detector technology, a
lightweight, high performance device would allow PET brain imaging in
different environments and during behavioral tasks. Such a wearable
system that allows the subjects to move their heads and walk-the
Ambulatory Microdose PET (AM-PET)-is currently under development. This
imager will be helpful for testing subjects performing selected
activities such as gestures, virtual reality activities and walking. The
need for this type of lightweight mobile device has led to the
construction of a proof of concept portable head-worn unit that uses
twelve silicon photomultiplier (SiPM) PET module sensors built into a
small ring which fits around the head. This paper is focused on the
engineering design of mechanical support aspects of the AM-PET project,
both of the current device as well as of the coming next-generation
devices. The goal of this work is to optimize design of the scanner and
its mechanics to improve comfort for the subject by reducing the effect
of weight, and to enable diversification of its applications amongst
different research activities.
- PMID: 28534848
- DOI: 10.3390/s17051164
