Efficacité d'une intervention psychologique assistée par robot pour les enfants avec un diagnostic de troubles du spectre de l'autisme

Aperçu: G.M.

Les difficultés d'interaction sociale caractérisent les enfants avec un diagnostic de "troubles du spectre de l'autisme" (dTSA) et ont un impact négatif sur leur vie quotidienne. L'intégration d'un robot social-humanoïde dans le traitement clinique standard s'est avérée prometteuse.
L'objectif principal de cette étude contrôlée randomisée était d'évaluer l'efficacité d'une intervention psychosociale assistée par robot et l'objectif secondaire était d'étudier les différences potentielles entre un groupe d'intervention assistée par robot et un groupe témoin recevant une intervention humaine uniquement.
L'analyse des résultats a montré que l'intervention assistée par robot pouvait être bénéfique en améliorant les compétences psychosociales des enfants. Cette amélioration a été mise en évidence par les tests neuropsychologiques et les rapports des parents.
La comparaison des groupes n'a présenté que des différences statistiquement significatives minimes. L'étude souligne le potentiel des interventions assistées par robot pour augmenter les soins standard.

. 2022 Nov 4.

doi: 10.1007/s10803-022-05796-5. Online ahead of print.

Effectiveness of a Robot-Assisted Psychological Intervention for Children with Autism Spectrum Disorder

Vasiliki Holeva  ¹ , V A Nikopoulou  ² , C Lytridis  ³ , C Bazinas  ³ , P Kechayas  ² , G Sidiropoulos  ³ , M Papadopoulou  ⁴ , M D Kerasidou  ² , C Karatsioras  ⁵ , N Geronikola  ⁶ , G A Papakostas  ³ , V G Kaburlasos  ³ , A Evangeliou  ⁴

Affiliations

• PMID: 36331688
• DOI: 10.1007/s10803-022-05796-5

Abstract

Difficulties with social interaction characterise children with Autism Spectrum Disorders and have a negative impact in their everyday life. Integrating a social-humanoid robot within the standard clinical treatment has been proven promising. The main aim of this randomised controlled study was to evaluate the effectiveness of a robot-assisted psychosocial intervention and the secondary aim was to investigate potential differences between a robot-assisted intervention group and a control group receiving intervention by humans only. The analysis of the results showed that robot-assisted intervention could be beneficial by improving children's psychosocial skills. This improvement was highlighted by neuropsychological testing and parent reporting. Group comparison only presented minimal statistically significant differences. The study underpins the potential of robot-assisted interventions to augment standard care.

Keywords: Autism spectrum disorders; Human–robot interaction; Psychological intervention; Randomised controlled trial; Robot-assisted therapy.

© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

References

1. 1. Achenbach, T. M., & Rescorla, L. A. (2001). Manual for the ASEBA School-Age Forms & Profiles. University of Vermont, Research Center for Children, Youth, & Families.
2. 1. Alabdulkareem, A., Alhakbani, N., & Al-Nafjan, A. (2022). A systematic review of research on robot-assisted therapy for children with autism. Sensors, 22(3), 944. https://doi.org/10.3390/s22030944 - DOI - PubMed - PMC
3. 1. Altschuler, M., Sideridis, G., Kala, S., Warshawsky, M., Gilbert, R., Carroll, D., Burger-Caplan, R., & Faja, S. (2018). Measuring individual differences in cognitive, affective, and spontaneous theory of mind among school-aged children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 48(11), 3945–3957. https://doi.org/10.1007/s10803-018-3663-1 - DOI - PubMed - PMC
4. 1. Amirova, A., Rakhymbayeva, N., Yadollahi, E., Sandygulova, A., & Johal, W. (2021). 10 Years of Human-NAO Interaction Research: A Scoping Review. Frontiers in Robotics and AI, 8, 744526. https://doi.org/10.3389/frobt.2021.744526 - DOI - PubMed - PMC
5. 1. Baron-Cohen, S., Leslie, A. M., & Frith, U. (1985). Does the autistic child have a “theory of mind”? Cognition, 21(1), 37–46. https://doi.org/10.1016/0010-0277(85)90022-8 - DOI - PubMed
6. 1. Begeer, S., Gevers, C., Clifford, P., Verhoeve, M., Kat, K., Hoddenbach, E., & Boer, F. (2011). Theory of mind training in children with autism: A randomized controlled trial. Journal of Autism and Developmental Disorders, 41(8), 997–1006. https://doi.org/10.1007/s10803-010-1121-9 - DOI - PubMed
7. 1. Begum, M., Serna, R. W., & Yanco, H. A. (2016). Are robots ready to deliver autism interventions? A comprehensive review. International Journal of Social Robotics, 8(2), 157–181. https://doi.org/10.1007/s12369-016-0346-y - DOI
8. 1. Bekele, E. T., Crittendon, J. A., Swanson, A. R., Sarkar, N., & Warren, Z. E. (2014). Pilot clinical application of an adaptive robotic system for young children with autism. Autism, 18, 598–608. https://doi.org/10.1177/1362361313479454 - DOI - PubMed
9. 1. Boccanfuso, L., Scarborough, S., Abramson, R. K., Hall, A. V., Wright, H. H., & O’Kane, J. M. (2017). A low-cost socially assistive robot and robot-assisted intervention for children with autism spectrum disorder: Field trials and lessons learned. Autonomous Robots, 41(3), 637–655. https://doi.org/10.1007/s10514-016-9554-4 - DOI
10. 1. Conti, D., Trubia, G., Buono, S., Di Nuovo, S., & Di Nuovo, A. (2019). Affect Recognition in Autism: A single case study on integrating a humanoid robot in a standard therapy. Qwerty-Open and Interdisciplinary Journal of Technology, Culture and Education, 14(2), 66–87. - DOI
11. 1. Costescu, C. A., Vanderborght, B., & David, D. O. (2014). The effects of robot-enhanced psychotherapy: A meta-analysis. Review of General Psychology, 18(2), 127–136. https://doi.org/10.1037/gpr0000007 - DOI
12. 1. Demetriou, E. A., DeMayo, M. M., & Guastella, A. J. (2019). Executive function in autism spectrum disorder: History, theoretical models, empirical findings, and potential as an endophenotype. Frontiers in Psychiatry. https://doi.org/10.3389/fpsyt.2019.00753 - DOI - PubMed - PMC
13. 1. Diehl, J. J., Schmitt, L. M., Villano, M., & Crowell, C. R. (2012). The clinical use of robots for individuals with autism spectrum disorders: A critical review. Research in Autism Spectrum Disorders, 6(1), 249–262. https://doi.org/10.1016/j.rasd.2011.05.006 - DOI - PubMed - PMC
14. 1. Duradoni, M., Colombini, G., Russo, P. A., & Guazzini, A. (2021). Robotic Psychology: A PRISMA Systematic Review on Social-Robot-Based Interventions in Psychological Domains. Journal MDPI, 4(4), 664–697. https://doi.org/10.3390/j4040048 - DOI
15. 1. Gasser, G. (2021). The dawn of social robots: Anthropological and ethical issues. Minds and Machines, 31(3), 329–336. https://doi.org/10.1007/s11023-021-09572-9 - DOI
16. 1. Ghiglino, D., Chevalier, P., Floris, F., Priolo, T., & Wykowska, A. (2021). Follow the white robot: Efficacy of robot-assistive training for children with autism spectrum disorder. Research in Autism Spectrum Disorders, 86, 101822. https://doi.org/10.1016/j.rasd.2021.101822 - DOI
17. 1. Goodman, R. (1997). The Strengths and Difficulties Questionnaire: A research note. Journal of Child Psychology and Psychiatry, 38(5), 581–586. - DOI - PubMed
18. 1. Gubenko, A., Kirsch, C., Smilek, J. N., Lubart, T., & Houssemand, C. (2021). Educational Robotics and Robot Creativity: An Interdisciplinary Dialogue. Frontiers in Robotics and AI, 8, 178. https://doi.org/10.3389/frobt.2021.662030 - DOI
19. 1. Heidari, R., Alipour, S., Meghdari, A., & Shehni Yailagh, M. (2019). The Impact Of Social Robots Intervention On Improving The Executive Functions In Children With Autism Disorder. Studies in Medical Sciences, 30(9), 744–752.
20. 1. Hill, E. L. (2004). Evaluating the theory of executive dysfunction in autism. Developmental Review, 24(2), 189–233. https://doi.org/10.1016/j.dr.2004.01.001 - DOI
21. 1. Holeva, V., Nikopoulou, V. A., Papadopoulou, M., Vrochidou, E., Papakostas, G. A., & Kaburlasos, V. G. (2019). Toward robot-assisted psychosocial intervention for children with Autism Spectrum Disorder (ASD). International Conference on Social Robotics. https://doi.org/10.1007/978-3-030-35888-4 - DOI
22. 1. Huskens, B., Verschuur, R., Gillesen, J., Didden, R., & Barakova, E. (2013). Promoting question-asking in school-aged children with autism spectrum disorders: Effectiveness of a robot intervention compared to a human-trainer intervention. Developmental Neurorehabilitation, 16(5), 345–356. - DOI - PubMed
23. 1. Ismail, L. I., Verhoeven, T., Dambre, J., & Wyffels, F. (2019). Leveraging robotics research for children with autism: A review. International Journal of Social Robotics, 11(3), 389–410. https://doi.org/10.1007/s12369-018-0508-1 - DOI
24. 1. Jurek, L., Baltazar, M., Gulati, S., Novakovic, N., Núñez, M., Oakley, J., & O’Hagan, A. (2021). Response (minimum clinically relevant change) in ASD symptoms after an intervention according to CARS-2: Consensus from an expert elicitation procedure. European Child & Adolescent Psychiatry. https://doi.org/10.1007/s00787-021-01772-z - DOI
25. 1. Kaburlasos, V., Holeva, V., Dardani, C., Papadopoulou, M., Kechayas, P., Lytridis, C., Bazinas, C., Nikopoulou, V. A. (2020, June 3). A Feasibility Study to Evaluate the Application of a Robot-Assisted ASD Intervention in Greece. [Poster presentation]. International Society for Autism Research 2020, Virtual.
26. 1. Kim, S., Hirokawa, M., Matsuda, S., Funahashi, A., & Suzuki, K. (2021). Smiles as a signal of prosocial behaviors toward the robot in the therapeutic setting for children with autism spectrum disorder. Frontiers in Robotics and AI, 8, 599755. https://doi.org/10.3389/frobt.2021.599755 - DOI - PubMed - PMC
27. 1. Kouroupa, A., Laws, K. R., Irvine, K., Mengoni, S. E., Baird, A., & Sharma, S. (2022). The use of social robots with children and young people on the autism spectrum: A systematic review and meta-analysis. PLoS ONE, 17(6), e0269800. https://doi.org/10.1371/journal.pone.0269800 - DOI - PubMed - PMC
28. 1. Korkman, M., Kirk, U., & Kemp, S. (2007). NEPSY-II (2nd edn.). Harcourt Assessment.
29. 1. Kumazaki, H., Muramatsu, T., Yoshikawa, Y., Matsumoto, Y., Ishiguro, H., Kikuchi, M., Sumiyoshi, T., & Mimura, M. (2020). Optimal robot for intervention for individuals with autism spectrum disorders. Psychiatry and Clinical Neurosciences, 74(11), 581–586. https://doi.org/10.1111/pcn.13132 - DOI - PubMed - PMC
30. 1. Leaf, J. B., Cihon, J. H., Leaf, R., McEachin, J., Liu, N., Russell, N., Unumb, L., Shapiro, S., & Khosrowshahi, D. (2021). Concerns About ABA-Based Intervention: An Evaluation and Recommendations. Journal of Autism and Developmental Disorders. https://doi.org/10.1007/s10803-021-05137-y - DOI - PubMed - PMC
31. 1. Lebersfeld, J., Brasher, C. J., Clesi, C. D., Stevens, C. E., Biasini, F. J., & Hopkins, M. I. (2018). 2157 the socially animated machine (sam) robot: A social skills intervention for children with autism spectrum disorder. Journal of Clinical and Translational Science, 2(S1), 49–49. https://doi.org/10.1017/cts.2018.190 - DOI - PMC
32. 1. Leung, R. C., Vogan, V. M., Powell, T. L., Anagnostou, E., & Taylor, M. J. (2016). The role of executive functions in social impairment in Autism Spectrum Disorder. Child Neuropsychology, 22(3), 336–344. https://doi.org/10.1080/09297049.2015.1005066 - DOI - PubMed
33. 1. Li, Q., Liu, P., Yan, N., & Feng, T. (2020). Executive function training improves emotional competence for preschool children: The roles of inhibition control and working memory. Frontiers in Psychology, 11, 347. https://doi.org/10.3389/fpsyg.2020.00347 - DOI - PubMed - PMC
34. 1. Lord, C., Elsabbagh, M., Baird, G., & Veenstra-Vanderweele, J. (2018). Autism spectrum disorder. The Lancet, 392(10146), 508–520. https://doi.org/10.1016/S0140-6736(18)31129-2 - DOI
35. 1. Lytridis, C., Bazinas, C., Sidiropoulos, G., Papakostas, G. A., Kaburlasos, V. G., Nikopoulou, V. A., Holeva, V., & Evangeliou, A. (2020). Distance special education delivery by social robots. Electronics, 9(6), 1034. - DOI
36. 1. Lytridis, C., Kaburlasos, V. G., Bazinas, C., Papakostas, G. A., Sidiropoulos, G., Nikopoulou, V. A., Holeva, V., Papadopoulou, M., & Evangeliou, A. (2022). Behavioral Data Analysis of Robot-Assisted Autism Spectrum Disorder (ASD) Interventions Based on Lattice Computing Techniques. Sensors, 22(2), 621. https://doi.org/10.3390/s22020621 - DOI - PubMed - PMC
37. 1. Marino, F., Chilà, P., Sfrazzetto, S. T., Carrozza, C., Crimi, I., Failla, C., Busà, M., Bernava, G., Tartarisco, G., Vagni, D., Ruta, L., & Pioggia, G. (2020). Outcomes of a robot-assisted social-emotional understanding intervention for young children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 50(6), 1973–1987. https://doi.org/10.1007/s10803-019-03953-x - DOI - PubMed
38. 1. Manzi, F., Peretti, G., Di Dio, C., Cangelosi, A., Itakura, S., Kanda, T., Ishiguro, H., Massaro, D., & Marchetti, A. (2020). A robot is not worth another: Exploring children’s mental state attribution to different humanoid robots. Frontiers in Psychology, 11, 2011. https://doi.org/10.3389/fpsyg.2020.02011 - DOI - PubMed - PMC
39. 1. Miranda, A., Berenguer, C., Roselló, B., Baixauli, I., & Colomer, C. (2017). Social cognition in children with high-functioning autism spectrum disorder and attention-deficit/hyperactivity disorder. Associations with executive functions. Frontiers in Psychology, 8, 1035. - DOI - PubMed - PMC
40. 1. Roski, J., Hamilton, B. A., Chapman, W., Heffner, J., Trivedi, R., Del Fiol, G., Kukafka, R., Bleicher, P., Estiri, H., Klann, J., & Pierce, J. (2019). How Artificial Intelligence is changing health and health care. In M. Matheny, S. T. Israni, M. Ahmed, & D. Whicher (Eds.), Artificial intelligence in health care: The hope, the hype, the promise, the peril (pp. 59–88). National Academy of Medicine.
41. 1. Nikopoulou, V. A., Holeva, V., Kerasidou, M. D., Kechayas, P., Papadopoulou, M., Vrochidou, E., Papakostas, G. A., & Kaburlasos, V. G. (2020). Identifying linguistic cues: Towards developing robots with empathy in autism interventions. Journal of Clinical Medicine of Kazakhstan, 2(56), 27–33. - DOI
42. 1. Ogawa, Y., Itani, O., Jike, M., & Watanabe, N. (2021). Psychosocial Interventions for Employment of Individuals with Autism Spectrum Disorder: A Systematic Review and Meta-analysis of Randomized Clinical Trials. Review Journal of Autism and Developmental Disorders. https://doi.org/10.1007/s40489-021-00285-4 - DOI
43. 1. Olde Dubbelink, L. M. E., & Geurts, H. M. (2017). Planning Skills in Autism Spectrum Disorder across the Lifespan: A Meta-Analysis and Meta-Regression. Journal Autism Developmental Disorder, 47, 1148–1165. https://doi.org/10.1007/s10803-016-3013-0 - DOI
44. 1. Ousley, O., & Cermak, T. (2014). Autism spectrum disorder: Defining dimensions and subgroups. Current Developmental Disorders Reports, 1(1), 20–28. https://doi.org/10.1007/s40474-013-0003-1 - DOI - PubMed
45. 1. Papakostas, G. A., Sidiropoulos, G. K., Papadopoulou, C. I., Vrochidou, E., Kaburlasos, V. G., Papadopoulou, M. T., Holeva, V., Nikopoulou, V. A., & Dalivigkas, N. (2021). Social Robots in Special Education: A Systematic Review. Electronics, 10(12), 1398. https://doi.org/10.3390/electronics10121398 - DOI
46. 1. Pennisi, P., Tonacci, A., Tartarisco, G., Billeci, L., Ruta, L., Gangemi, S., & Pioggia, G. (2016). Autism and social robotics: A systematic review. Autism Research, 9(2), 165–183. https://doi.org/10.1002/aur.1527 - DOI - PubMed
47. 1. Pinto Costa, A., Kirsten, L., Charpiot, L., & Steffgen, G. (2019). Mental health benefits of a robot-mediated emotional ability training for children with autism: An exploratory study. International Society for Autism Research. http://hdl.handle.net/10993/42945
48. 1. Pioggia, G., Sica, M. L., Ferro, M., Igliozzi, R., Muratori, F., Ahluwalia, A., & De Rossi, D. (2007). Human-robot interaction in autism: FACE, an android-based social therapy. International Workshop on Robot and Human Interactive Communication. https://doi.org/10.1109/ROMAN.2007.4415156 - DOI
49. 1. Politte, L. C., Howe, Y., Nowinski, L., Palumbo, M., & McDougle, C. J. (2015). Evidence-based treatments for autism spectrum disorder. Current Treatment Options in Psychiatry, 2(1), 38–56. https://doi.org/10.1007/s40501-015-0031-z - DOI
50. 1. Pop, C. A., Simut, R., Pintea, S., Saldien, J., Rusu, A., David, D., Vanderfaeillie, J., & lefeber, D., & Vanderborght, B. (2013). Can the social robot Probo help children with autism to identify situation-based emotions? A series of single case experiments. International Journal of Humanoid Robotics, 10(03), 1350025. https://doi.org/10.1142/S0219843613500254 - DOI
51. 1. Robinson, N. L., Cottier, T. V., & Kavanagh, D. J. (2019). Psychosocial health interventions by social robots: Systematic review of randomized controlled trials. Journal of Medical Internet Research, 21(5), e13203. https://doi.org/10.2196/13203 - DOI - PubMed - PMC
52. 1. Rogers, S. J., & Vismara, L. (2014). Interventions for infants and toddlers at risk for autism spectrum disorder. In F. R. Volkmar, R. Paul, S. J. Rogers, & K. A. Pelphrey (Eds.), Handbook of autism and pervasive developmental disorders: Diagnosis, development, and brain mechanisms (pp. 737–770). Wiley.
53. 1. Rosello, B., Berenguer, C., Baixauli, I., García, R., & Miranda, A. (2020). Theory of mind profiles in children with autism spectrum disorder: Adaptive/social skills and pragmatic competence. Frontiers in Psychology, 11, 1. - DOI
54. 1. Rutter, M., Le Couteur, A., & Lord, C. (2003). Autism diagnostic interview-revised. Western Psychological Services. https://doi.org/10.1007/978-1-4419-1698-3_894 - DOI
55. 1. Salimi, Z., Jenabi, E., & Bashirian, S. (2021). Are social robots ready yet to be used in care and therapy of autism spectrum disorder: A systematic review of randomized controlled trials. Neuroscience & Biobehavioral Reviews, 129, 1–16. https://doi.org/10.1016/j.neubiorev.2021.04.009 - DOI
56. 1. Salvador, M., Marsh, A. S., Gutierrez, A., & Mahoor, M. H. (2016). Development of an ABA autism intervention delivered by a humanoid robot. International Conference on Social Robotics. https://doi.org/10.1007/978-3-319-47437-3_54 - DOI
57. 1. Schadenberg, B. R., Reidsma, D., Heylen, D. K., & Evers, V. (2020). Differences in spontaneous interactions of autistic children in an interaction with an adult and humanoid robot. Frontiers in Robotics and AI, 7, 28. https://doi.org/10.3389/frobt.2020.00028 - DOI - PubMed - PMC
58. 1. Schopler, E., Van Bourgondien, M. E., Wellman, G. J., & Love, S. R. (2010). The Childhood Autism Rating Scale (2nd edn.) (CARS2). Western Psychological Services.
59. 1. Seida, J. K., Ospina, M. B., Karkhaneh, M., Hartling, L., Smith, V., & Clark, B. (2009). Systematic reviews of psychosocial interventions for autism: An umbrella review. Developmental Medicine & Child Neurology, 51(2), 95–104. https://doi.org/10.1111/j.1469-8749.2008.03211.x - DOI
60. 1. Soares, F. O., Costa, S. C., Santos, C. P., Pereira, A. P. S., Hiolle, A. R., & Silva, V. (2019). Socio-emotional development in high functioning children with Autism Spectrum Disorders using a humanoid robot. Interaction Studies, 20(2), 205–233. https://doi.org/10.1075/is.15003.cos - DOI
61. 1. Srinivasan, S. M., Park, I. K., Neelly, L. B., & Bhat, A. N. (2015). A comparison of the effects of rhythm and robotic interventions on repetitive behaviors and affective states of children with Autism Spectrum Disorder (ASD). Research in Autism Spectrum Disorders, 18, 51–63. https://doi.org/10.1016/j.rasd.2015.07.004 - DOI - PubMed - PMC
62. 1. Syriopoulou-Delli, C. K., & Gkiolnta, E. (2020). Review of assistive technology in the training of children with autism spectrum disorders. International Journal of Developmental Disabilities, 68(2), 73–85. https://doi.org/10.1080/20473869.2019.1706333 - DOI - PubMed - PMC
63. 1. van den Berk-Smeekens, I., van Dongen-Boomsma, M., De Korte, M. W., Den Boer, J. C., Oosterling, I. J., Peters-Scheffer, N. C., Buitelaar, J. K., Barakova, E. I., Lourens, T., Staal, W. G., & Glennon, J. C. (2020). Adherence and acceptability of a robot-assisted Pivotal Response Treatment protocol for children with autism spectrum disorder. Scientific Reports, 10(1), 8110. https://doi.org/10.1038/s41598-020-65048-3 - DOI - PubMed - PMC
64. 1. Wechsler, D. (2014). Wechsler intelligence scale for children (5th ed.). NCS Pearson.
65. 1. Wechsler, D. (2012). Wechsler Preschool and Primary Scale of Intelligence (4th ed.). NCS Pearson.
66. 1. Weiss, J. A., Thomson, K., Burnham Riosa, P., Albaum, C., Chan, V., Maughan, A., Tablon, P., & Black, K. (2018). A randomized waitlist-controlled trial of cognitive behavior therapy to improve emotion regulation in children with autism. Journal of Child Psychology and Psychiatry, 59(11), 1180–1191. https://doi.org/10.1111/jcpp.12915 - DOI - PubMed
67. 1. Yuan, F., Klavon, E., Liu, Z., Lopez, R. P., & Zhao, X. (2021). A systematic review of robotic rehabilitation for cognitive training. Frontiers in Robotics and AI, 8, 105. https://doi.org/10.3389/frobt.2021.605715 - DOI
68. 1. Yun, S. S., Choi, J., Park, S. K., Bong, G. Y., & Yoo, H. (2017). Social skills training for children with autism spectrum disorder using a robotic behavioral intervention system. Autism Research, 10(7), 1306–1323. https://doi.org/10.1002/aur.1778 - DOI - PubMed
69. 1. Zhang, Y., Song, W., Tan, Z., Zhu, H., Wang, Y., Lam, C. M., Wang, Y., Hoi, P. S., Lu, H., Chan, B. S., Chen., J., & Yi, L. (2019). Could social robots facilitate children with autism spectrum disorders in learning distrust and deception? Computers in Human Behavior, 98, 140–149. https://doi.org/10.1016/j.chb.2019.04.008 - DOI