Atténuation de la fonction sociale chez les jeunes femmes ayant une Anorexie nerveuse récente et des personnes rétablies

Aperçu: G.M.

Un sous-groupe de personnes souffrant d'anorexie mentale (AN) présente des difficultés sociales; Cependant, il n'est pas clair si les personnes avec un une comorbidite de TSA expliquent ces difficultés. 

L'étude a porté sur 43 jeunes femmes ayant eu un premier épisode anorexique sans TSA, 23 personnes ayant récupéré à l'adolescente d'une anorexie et 41 sans troubles.

Les participants ayant un premier épisode AN et ceux ayant récupéré d'une AN ont présenté des difficultés dans la fonction sociale, qui n'étaient pas associées à l'indice de masse corporelle ou à d'autres facteurs liés à un trouble chez les patients ayant un premier épisode AN. Les troubles de l'humeur et l'anxiété n'étaient pas associés à ces difficultés. 

Finalement, seuls les participants se sont remis de l'AN ont démontré des déficits dans des domaines spécifiques de la cognition sociale: perception de gestes corporels non verbaux et prosodie vocale. 

J Adolesc Health. 2017 Jan;60(1):23-32. doi: 10.1016/j.jadohealth.2016.08.011. Epub 2016 Oct 27.

Impairment of Social Function in Young Females With Recent-Onset Anorexia Nervosa and Recovered Individuals

Bentz M¹, Jepsen JR², Pedersen T³, Bulik CM⁴, Pedersen L⁵, Pagsberg AK⁶, Plessen KJ⁶.

Author information

1

Child and Adolescent Mental Health Centre, Mental Health Services in the Capital Region of Denmark, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: mette.bentz@regionh.dk

2

Child and Adolescent Mental Health Centre, Mental Health Services in the Capital Region of Denmark, Copenhagen, Denmark; Lundbeck Foundation Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research (CINS), Psychiatric Center, Glostrup, Denmark; Center for Neuropsychiatric Schizophrenia Research (CNSR), Psychiatric Center, Glostrup, Denmark.

3

Child and Adolescent Mental Health Centre, Mental Health Services in the Capital Region of Denmark, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.

4

Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

5

Center for Autisme, Herlev, Denmark.

6

Child and Adolescent Mental Health Centre, Mental Health Services in the Capital Region of Denmark, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Abstract

PURPOSE:

A subgroup of individuals with anorexia nervosa (AN) displays social difficulties; however, it is not clear if individuals with comorbid autism spectrum disorders account for these difficulties.


METHODS:

We compared social function using the Autism Diagnostic Observation Schedule in 43 young females with first-episode AN who did not have comorbid autism spectrum disorder, 28 individuals recovered from adolescent-onset AN, and 41 healthy comparison individuals (age range 14-22 years). We measured adaptive behavior with the Vineland-II parent questionnaire, and aspects of social cognition with psychological tests, such as the Reading-the-Mind-in-the-Eyes test, Profile of Nonverbal Sensitivity short version, The Awareness of Social Inference Test, Animated Triangles, and the CANTAB Affective Go/No-go task.


RESULTS:

Participants with first-episode AN and those recovered from AN displayed difficulties in social function, which were not associated with body mass index or other state factors of the disorder in those with first-episode AN. Mood problems and anxiety were not associated with these difficulties. Parents rated participants with first-episode AN lower than recovered and control participants on the Socialization Domain of Vineland-II. Finally, only participants recovered from AN demonstrated deficits in specific domains of social cognition: perceiving nonverbal bodily gesture and vocal prosody.


CONCLUSIONS:

Young females with first-episode AN and those recovered from AN displayed impairments in social function, which may represent more stable traits of the disorder. Only participants recovered from AN demonstrated deficits in social cognition.


Copyright © 2016 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

PMID: 28341015

DOI: 10.1016/j.jadohealth.2016.08.01