Aperçu: G.M.
Une interprétation précise et une expression appropriée des émotions sont des aspects clés de la connaissance sociale. Plusieurs
troubles mentaux sont caractérisés par des difficultés
transdiagnostiques dans ces domaines et, récemment, il y a eu un intérêt
croissant à explorer les effets de l'ocytocine sur le fonctionnement
socio-émotionnel. Cette revue comprend 33 études. Quinze
des études comprenaient des personnes avec un diagnostic de trouble du spectre
de l'autisme, de schizophrénie, de trouble de la personnalité limite,
de démence frontotemporelle, d'anorexie mentale, de boulimie
mentale, du syndrome de stress post-traumatique, de dépression et de dépendance aux opioïdes et à l'alcool.
Une
seule dose d'oxytocine intranasale a considérablement amélioré la
reconnaissance des émotions de base, en particulier la peur, et a
augmenté l'expression d'émotions positives chez les personnes en bonne
santé.
L'ocytocine
n'a pas influencé de manière significative la théorie de l'esprit ni
l'expression d'émotions négatives chez les personnes en bonne santé.
Enfin, l'ocytocine intranasale n'a pas eu d'influence significative
sur l'interprétation ou l'expression d'émotions chez les populations
cliniques.
Neurosci Biobehav Rev. 2017 Apr 30. pii: S0149-7634(16)30744-8. doi: 10.1016/j.neubiorev.2017.04.010.
Meta-analysis of the effects of intranasal oxytocin on interpretation and expression of emotions
Leppanen J1, Ng KW2, Tchanturia K3, Treasure J4.
Author information
- 1
- King's College London, Institute of Psychiatry, Psychology, and Neuroscience, Department of Psychological Medicine, London, United Kingdom. Electronic address: jenni.leppanen@kcl.ac.uk
- 2
- Singapore General Hospital,20 College Road, Academia, 169865, Singapore.
- 3
- King's College London, Institute of Psychiatry, Psychology, and Neuroscience, Department of Psychological Medicine, London, United Kingdom; Department of Psychology, Illia State University, Tbilisi, Georgia.
- 4
- King's College London, Institute of Psychiatry, Psychology, and Neuroscience, Department of Psychological Medicine, London, United Kingdom.
Abstract
Accurate
interpretation and appropriate expression of emotions are key aspects
of social-cognition. Several mental disorders are characterised by
transdiagnostic difficulties in these areas and, recently, there has
been increasing interest in exploring the effects of oxytocin on
social-emotional functioning. This review consists of 33 studies.
Fifteen of the studies included people with autism spectrum disorder,
schizophrenia, borderline personality disorder, frontotemporal dementia,
anorexia nervosa, bulimia nervosa, post-traumatic stress disorder,
depression, and opioid and alcohol dependence. We conducted ten
meta-analyses examining the effects of intranasal oxytocin on expression
of emotions, emotional theory of mind, sensitivity to recognise basic
emotions, and recognition of basic emotions. A single dose of intranasal
oxytocin significantly improved the recognition of basic emotions,
particularly fear, and increased the expression of positive emotions
among the healthy individuals. Oxytocin did not significantly influence
theory of mind or the expression of negative emotions among the healthy
individuals. Finally, intranasal oxytocin did not significantly
influence interpretation or expression of emotions among the clinical
populations.
Copyright © 2017. Published by Elsevier Ltd.
- PMID:28467893
- DOI: 10.1016/j.neubiorev.2017.04.010
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