Prévalence et caractéristiques des troubles du spectre de l'autisme chez les enfants avec une paralysie cérébrale

Aperçu: G.M.

L'étude a pour objectif d'évaluer la prévalence des troubles du spectre de l'autisme (TSA) co-occurrents chez les enfants avec une paralysie cérébrale (CP) et décrire leurs caractéristiques.

Parmi les enfants avec CP, 107 avaient un diagnostic associé de TSA - soit 8.7% de la population étudiée. Cette proportion variait selon les centres de 4,0% à 16,7%, mais était indépendante de la prévalence du CP.  

Le sexe masculin, l'épilepsie coexistant, le handicap intellectuel et une meilleure aptitude à la marche étaient associés à la coexistence des TSA.

Dev Med Child Neurol. 2017 Apr 25. doi: 10.1111/dmcn.13436.

Prevalence and characteristics of autism spectrum disorders in children with cerebral palsy

Delobel-Ayoub M^1,2,3, Klapouszczak D^1,2,3, van Bakel MME⁴, Horridge K⁵, Sigurdardottir S⁶, Himmelmann K⁷, Arnaud C^1,2,3.

Author information

1

Inserm UMR 1027, Toulouse, France.

2

Université de Toulouse III, Toulouse, France.

3

CHU Toulouse, Registre des Handicaps de l'Enfant en Haute-Garonne, Toulouse, France.

4

Register for Severely Disabled Children and Perinatal Observatory, Grenoble, France.

5

Paediatric Disability Department, Sunderland Royal Hospital, Sunderland, UK.

6

The State Diagnostic and Counselling Centre, Kopavogur, Iceland.

7

Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Abstract

AIM:

To evaluate the prevalence of co-occurring autism spectrum disorders (ASDs) among children with cerebral palsy (CP), and to describe their characteristics.

METHOD:

The data of 1225 CP cases from four population-based registers (Iceland, Sweden, and two in France) and one population-based surveillance programme (North East England, UK) participating in the Surveillance of Cerebral Palsy in Europe Network (SCPE) were analysed. The ASD diagnoses were systematically recorded using category F84 of the International Classification of Diseases, 10th Revision. The registers provided data on children born between 1995 and 2006, while the cross-sectional survey in the UK concerned children aged 0 to 19 years, registered in 2010.

RESULTS:

Among the children with CP, 107 had an associated diagnosis of ASD - i.e., 8.7% of the study population (95% confidence interval 7.2-10.5). This proportion varied across centres from 4.0% to 16.7% but was independent of CP prevalence. Male sex, co-occurring epilepsy, intellectual disability, and better walking ability were associated with the coexistence of ASD.

INTERPRETATION:

Our findings support the need for a multidisciplinary approach to management of children with CP to adequately identify and address all facets of presentation, including ASD.

© 2017 Mac Keith Press.

PMID: 28439889

DOI: 10.1111/dmcn.13436